BRAVECTO 112,5mg for dogs 2-4,5Kg – 2 chewable tablets

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Bravecto 112.5 mg chewable tablets for very small dogs from 2 to 4.5 kg In dogs: treatment of tick and flea infestations. This drug is a systemic insecticide and acaricide that provides : immediate and persistent insecticidal activity on fleas (Ctenocephalides felis) for 12 weeks, immediate and persistent acaricidal activity on ticks for 12 weeks for Ixodes ricinus, Dermacentor reticulatus and Dermacentor variabilis, and for 8 weeks for Rhipicephalus sanguineus. In order to be exposed to the active substance, fleas and ticks must be present on the animal and have begun feeding. The effect on fleas begins within 8 hours (C. felis) and within 12 hours for ticks (I. ricinus). The product can be used as part of a treatment plan for Flea Allergy Dermatitis (FAD). Properties: Fluralaner is an acaricide and insecticide. It is effective against ticks and fleas in dogs. It is systemically active on target parasites. It potently inhibits certain parts of the arthropod nervous system through an antagonistic action on chloride channels (GABA receptor and glutamate receptor). The product helps control flea populations in areas to which treated dogs have access. An in vitro study has shown that very low concentrations of fluralaner stop the production of viable eggs by fleas. The flea's life cycle is disrupted due to the rapid onset of action and long-lasting effect against adult fleas on the animal and the absence of viable egg production. Fluralaner is readily absorbed after oral administration, reaching peak plasma concentrations within 1 day. Food enhances absorption. Fluralaner is excreted unchanged in the faeces (around 90% of the dose). Renal elimination is the minor route of elimination.